Medical Research

Cholecystectomy and NAFLD: does gallbladder removal have metabolic consequences?

Abstract Pathogenesis of nonalcoholic fatty liver (NAFLD) disease and gallbladder (GB) disease secondary to cholesterol gallstones is complex, yet both conditions share similar associated risk factors, most of them related to the metabolic syndrome. Cholecystectomy, the best treatment for GB disease, is one of the most performed abdominal surgeries worldwide. In this issue of the […]

Relationship of non-alcoholic fatty liver disease with cholecystectomy in the US population

Abstract OBJECTIVES: Other than weight-related conditions, risk factors for non-alcoholic fatty liver disease (NAFLD) are not well defined. We investigated the association of gallstones and cholecystectomy with NAFLD in a large, national, population-based study. METHODS: Among adult participants in the third US National Health and Nutrition Examination Survey, 1988-1994, ultrasonography for gallstone disease was performed, […]

Gallbladder Removal Raises Colon Cancer Risk

NEW YORK (Reuters Health) – Gallbladder removal or “cholecystectomy” raises the risk of colon but not rectal cancer, results of a UK study suggest. Still, experts note that the risk is only slightly increased and, therefore, should not influence the decision to undergo this procedure if it’s necessary. The findings support the view of previous […]

Nerves and Hormones Interact to Control Gallbladder Function

Gary M. Mawe PhysiologyPublished 1 April 1998Vol. 13no. 2,84-90 Figures & Data Info  PDF  ABSTRACT Ganglia are the target of several regulatory inputs to the gallbladder. Hormonal cholecystokinin and sympathetic nerves can up- or downregulate neurotransmission in the gallbladder, respectively, by altering the rate of acetylcholine release from vagal preganglionic terminals. Peptides released from sensory axons act directly […]

Dissolution of human brown pigment biliary stones

Abstract The chemical dissolution of human brown pigment stones was studied using various monophasic multicomponent solvents. Among the nine solutions tested for stone powder dissolution capacity, the two most active were retained for further analysis. The solvent containing 26 mM ethylenediaminetetraacetate, 40 mM sodium deoxycholate, 10 mM monoolein and 30% dimethylsulfoxide was efficient for calcium […]

Gastric complaints or postcholecystectomy syndrome?

Abstract Postcholecystectomy syndrome (PCS) is a complex of symptoms from gastrointestinal tract that could develop and maintain after cholecystectomy. PCS usually consists of: abdominal pain or colic, dyspepsia, constipation or diarrhoea, nausea, bloating, fatty food intolerance. Regarding PSC as disease entity is still a point of many controversies. THE AIM OF THE STUDY: To estimate […]

Relationship of Non-alcoholic Fatty Liver Disease With Cholecystectomy in the US Population

OBJECTIVES: Other than weight-related conditions, risk factors for non-alcoholic fatty liver disease (NAFLD) are not well defined. We investigated the association of gallstones and cholecystectomy with NAFLD in a large, national, population-based study. METHODS: Among adult participants in the third US National Health and Nutrition Examination Survey, 1988 – 1994, ultrasonography for gallstone disease was […]