Gallstone Root Cause & Treatment

Low phospholipid associated cholelithiasis: association with mutation in theMDR3/ABCB4 gene

Orphanet J Rare Dis. 2007; 2: 29. Published online 2007 Jun 11. doi:  10.1186/1750-1172-2-29 PMCID: PMC1910597 Olivier Rosmorduc1 and Raoul Poupon1 This article has been cited by other articles in PMC. Abstract Low phospholipid-associated cholelithiasis (LPAC) is characterized by the association of ABCB4 mutations and low biliary phospholipid concentration with symptomatic and recurring cholelithiasis. This syndrome is infrequent and corresponds to a peculiar small […]

MDR3 Deficiency – a root cause of gallstones

MDR3 Deficiency NORD gratefully acknowledges Prof. Emmanuel Jacquemin and Dr Emmanuel Gonzales, Pediatric Hepatology Unit and Pediatric Liver Transplantation Unit, Reference Center for Children with Biliary Atresia, Bicêtre Hospital, Paris, France, for assistance in the preparation of this report. Subdivisions of MDR3 Deficiency Low Phospholipid Associated Cholelithiasis Progressive Familial Intrahepatic Cholestasis Type 3 (PFIC3) General […]

Gallstones: Pathogenesis and Treatment

Very good background – unable to find an original

Evidence – Surgions don’t have a clue about treating gallstones

Treatment of cholelithiasis Ever wondered why, 1] Why, after 100+ odd years of medical research, medical industry has not come up with a holistic health plan / treatment solution for for gallstones and or gallbladder disease 2] Why, in the US more than twice as likely to undergo gallbladder surgery that in UK [ US […]